My Wellness Train Network

Menu 1
Menu 2
Menu 3
Menu 4
Menu 5
Menu 6

April 18.2025

2 Minutes Read

Exploring Pig Kidney Transplants: What It Means for Kidney Disease Patients

Medical researchers study a pig kidney in a lab, highlighting transplant challenges.

Historic Moment in Xenotransplantation: A New Hope for Kidney Failure

The recent removal of a genetically modified pig's kidney from Towana Looney, a 53-year-old woman from Alabama, marks an important chapter in the field of xenotransplantation. This groundbreaking procedure demonstrates both the possibilities and challenges of using animal organs for human transplants.

Patient Experience: A Mixed Outcome

Looney experienced a remarkable 130 days with her transplant—the longest duration documented for a genetically altered pig kidney. Initially, she could enjoy a life unrestrained by dialysis treatments, saying, "For the first time since 2016, I enjoyed time with friends and family without planning around dialysis treatments." Despite the eventual organ rejection, Looney's story highlights the potential impact of xenotransplantation on improving the quality of life for individuals with kidney failure.

Insights into Organ Rejection

Following her surgery, Looney began to experience rejection signals through elevated creatinine levels, leading to her return to dialysis. Although doctors suggested that additional immunosuppressive medications might have helped preserve the kidney, Looney and her medical team prioritized safety, ultimately opting not to pursue aggressive treatments. Dr. Robert Montgomery, who led the transplant at NYU Langone, reassured that this removal represents progress, stating, "This game is going to be won by incremental improvements..."

Future of Pig Kidney Transplantation

United Therapeutics Corporation, which engineered the pig used in Looney's transplant, plans to initiate a clinical trial later this year. This trial aims to recruit six patients and eventually expand to fifty, reflecting growing interest in xenotransplantation as a potential solution for the organ shortage crisis. Currently, over 550,000 people in the U.S. are facing kidney failure, and with fewer than 25,000 transplants performed in the last year, innovative approaches like pig organ transplantation could provide much-needed relief.

Navigating Kidney Health

For individuals facing kidney issues, understanding treatment options is critical. It is essential to stay informed about new advancements in medical technology, including the potential role of genetically-modified organs. As more clinical trials emerge, patients should consult healthcare providers about qualified options tailored to their health needs. Additionally, being aware of medication side effects, dosage guidelines, and potential treatments is vital in managing health effectively.

If you want to learn more about the evolving landscape of kidney health and treatments, contact us for more details.

Healthy Aging and Longevity

125 Views

0 Comments

Write A Comment

Please complete the captcha to submit your comment.

Related Posts All Posts

08.09.2026

Rising Patient Portal Messages Challenge Doctors: What You Need to Know

Update Understanding the Surge in Patient Portal Messages The healthcare landscape continues to evolve, particularly with increased reliance on digital communication tools. A recent report indicates that the number of messages sent through patient portals has doubled, presenting new challenges for healthcare providers. Doctors, who are already pressed for time, now face a growing workload as they try to keep up with the influx of messages from patients seeking information, advice, and clarifications concerning their health. The Challenges of Increased Communication This surge in patient interactions through portals can be viewed positively, as it indicates a higher level of patient engagement. However, it also means that healthcare professionals must balance effective communication with their clinical responsibilities. As patients seek more information about their medications, including everything from common medication side effects to how to read a prescription label, doctors are navigating a complex array of queries. Impact on Patient Care The rise in messages poses the risk of physician burnout, potentially impacting the quality of care patients receive. Their time is being stretched as they manage not only patient inquiries but also critical tasks such as reviewing FDA drug approvals and considering drug safety information before making clinical decisions. With an ever-increasing digital footprint, it's vital that healthcare systems find effective ways to manage these communications without compromising patient care. What Patients Can Do Patients must be mindful of the messages they send and consider which questions are urgent or necessary. Utilizing available resources such as medication side effects information, drug interaction checkers, and educational materials about over-the-counter medications can empower patients to find answers independently while allowing healthcare providers to focus on more critical tasks. Get Informed Staying informed about your health—including understanding prescription drug information and natural alternatives to medications—can foster better communication with your healthcare provider and improve your overall health outcomes. If you have further questions or need detailed inquiries answered, contact us for more details.

08.07.2026

How Rising Patient Portal Messages Impact Doctor Workloads and Care Quality

Update The Rise of Patient Portal Messages and Its Impact on HealthcareOver the past five years, the landscape of patient communication has evolved dramatically, with a significant doubling of messages sent through patient portals. According to a recent study from NYU Langone Health, these messages surged by 153% from 2020 to 2025, with around 1.34 billion messages exchanged—offering patients unprecedented access to their healthcare providers.However, this rise in communication does not equate to fewer in-person visits. In fact, the average number of office visits per patient has also increased, demonstrating that while patients are utilizing digital methods, they still depend on traditional care models. As a result, physicians are experiencing heightened workloads, leading to concerns over burnout and the sustainability of patient care.Understanding the New Patient-Physician DynamicThe shift from occasional contact to everyday communication through patient portals has significant implications. With the capability to request prescription refills, inquire about test results, and more, patients have become significantly more engaged in their health journeys. However, this increased demand can lead to a chronic stress burden on physicians, who must manage these messages alongside their regular tasks.Each incoming message—whether it’s a simple request for assistance or a complex query—requires careful attention and often, a time-consuming response. This reality has blurred the lines between a physician’s professional and personal life, leading many doctors to check messages late into the evening or during weekends, thus contributing to a phenomenon known as digital fatigue.Strategies to Alleviate Physician WorkloadTo mitigate the pressures associated with the growing volume of portal messages, healthcare systems are encouraged to implement several strategies. Maintaining clear communication guidelines that set expectations about response times can significantly reduce unnecessary patient inquiries.Additionally, delegating message triage to trained nurses or medical assistants can help alleviate the burden on physicians, directing routine inquiries away from already taxed doctors. Some healthcare providers also utilize automated response systems and symptom-checking tools to guide patients in making more informed decisions about when to reach out for help.Recognizing the Hidden Costs of Digital CommunicationThe ongoing rise in digital communication reflects a shift toward a more informed patient population, but it’s essential to recognize the hidden costs, including stress and burnout among healthcare professionals. As these pressures mount, there is an urgent need for healthcare organizations to address the demands of after-hours communications.Establishing designated quiet hours, streamlining workflows, and adopting technologies that prioritize efficiency can all serve to protect physician well-being. The time for systemic change is now; redefining how patient-physician communications are managed is pivotal for sustaining high-quality patient care in a technologically driven world.

08.07.2026

Midlife Strength Training: A Simple Strategy to Lower Your Diabetes Risk

Update Empower Your Health: Strength Training's Role in Preventing DiabetesAs we navigate the challenges of midlife, understanding how to maintain our health becomes increasingly important. A recent study indicates a strong link between midlife strength training and a reduced risk for developing type 2 diabetes. By focusing on resistance training, particularly during middle adulthood, individuals can significantly lower their chances of facing this health crisis.The Study's Key FindingsPublished in JAMA Network Open, the study followed over 143,000 adults for nearly two decades, revealing that those who engaged in at least two hours of resistance training per week saw a remarkable 27% decrease in their diabetes risk. This reduction soared to 42% among those who maintained a consistent strength training routine throughout their midlife. Dr. Shirin Jaggi, an endocrinologist at Northwell Health, emphasizes that while exercise has long been the bedrock of diabetes prevention, resistance training is particularly pivotal.Integrating Resistance Training into Your RoutineFor optimal results, the researchers suggest combining regular strength training with aerobic exercises and minimizing sedentary activities. It’s not just the volume of training that matters but also how consistently one maintains the regimen. Even allocating just one hour a week to resistance training can align with public health recommendations and yield substantial health benefits.Why This Matters NowThe relevance of diabetes prevention is more pressing than ever, especially as rates continue to rise among adults. As midlife approaches, having access to effective strategies for maintaining health is imperative. Resistance training not only fosters physical strength but also contributes positively to overall metabolic health.Consider This: Take ActionIncorporating strength training into your lifestyle doesn't have to be daunting. Start small and gradually build your regimen. Whether through home workouts, gym sessions, or classes, the important aspect is consistency. If you're seeking more detailed guidance on how to enhance your fitness journey or want to explore other aspects of health care, reach out to us for more information.

My Wellness Train Network

My Wellness Train Network News is a dynamic Wellness-focused Media News Platform dedicated to empowering individuals, healthcare professionals, and businesses in the health and wellness industry.

COMPANY

Home
Categories

984-238-6164

Raleigh, NC 27609

Available 24/7, delivering the best care anytime.

The information in these posts is for educational purposes only and is not intended as medical advice. Please consult a qualified healthcare professional for personalized guidance.

ABOUT US

My Wellness Train Network, with a focus on functional well-being, integrates medical science, nutrition, exercise, mental health, and lifestyle optimization to inspire and educate both professionals and the public.

{"company":"My Wellness Train","address":"1425 Falls Church Road","city":"Raleigh","state":"NC","zip":"27609","email":"trianglehwc@gmail.com","tos":"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","privacy":"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"}